Psychedelic Mental Health Institute
Psychedelic Mental Health Institute
Psychedelic Community of Practice & Research
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Psychedelic Mental Health Institute
Psychedelic Mental Health Institute

Psychedelic Mental Health Institute

About the Psychedelic Mental Health Institute
Collaborative psychotherapy in support of medicines that may affect mental health, including ketamine
Psychedelic Mental Health InstituteMichael DeMarco, PhD
Michael DeMarco, PhD | Life Coach, Psychedelic Ketamine Preparation & Integration, Sex Therapy
Mental health support through psychotherapy, life coaching, psychedelic ketamine preparation & integration, sex therapy
Life Coach, Psychedelic Ketamine Preparation & Integration, Sex Therapy

Mental health, Wellness, Psychedelic harm reduction coaching

Michael DeMarco, PhD
Remote Telehealth Life Coach | Rational Emotive Behavioral Coaching, Cognitive Behavioral Coaching | Board Certified Clinical Sexologist | Psychedelic Consultant & Integration Coach | Ketamine Preparation, Support and Integration Coach, Supervisor | Psychedelic Practitioner
Psychedelic Institute - Psychedelics in Mental HealthMichael DeMarco, PhD
INSTITUTO PSICODÉLICO DE SALUD MENTAL Y TERAPIA FAMILIAR
Un centro de estudios en psicodelia que aboga por el estudio y la práctica seguros y legales de las experiencias de la medicina psicodélica y su aplicación a la salud mental y el bienestar | Uruguay
Psychedelic Institute of Mental Health & Family TherapyMichael DeMarco, PhD

INSTITUTO PSICODÉLICO -- Un centro de estudios en psicodelia que aboga por el estudio y la práctica seguros y legales de las experiencias de la medicina psicodélica y su aplicación a la salud mental y el bienestar | Uruguay

Is ketamine a “psychedelic”?
Yes.
Psychedelic Institute of Mental Health & Family TherapyMichael DeMarco, PhD

Ketamine Psychedelic Preparation, Support & Integration

Psychedelic Cognitive Behavioral Therapy: On Ketamine, Context, and Competencies in “Assisted-Psychotherapy”
There are many tools to help a psychotherapist help clients learn to speak the language of cognitive behavioral therapy, especially tools which may help facilitate therapeutic alliance, including, but not limited to telehealth.
Psychedelic Institute of Mental Health & Family TherapyMichael DeMarco, PhD
Psychedelic Therapy: Does the psychedelic experience matter?
Psychedelic medicines have been studied in the Western medical literature consistently for over 100 years, over 60 of which in the ongoing study and practice of racemic ketamine. Psychedelic experiences are described similarly and often felt as profoundly meaningful.
Psychedelic Institute of Mental Health & Family TherapyMichael DeMarco, PhD
Neural correlates and subjective experiences in meditation vs psychedelics, including ketamine (Preliminary Lit Review)
A preliminary, evolving review of the literature. (Ongoing Draft) | Psychedelic Institute of Mental Health & Family Therapy
Psychedelic Institute of Mental Health & Family TherapyMichael DeMarco, PhD
Sublingual & Oral Ketamine Research: Efficacy, Dosage, and Treatment for Mental Health
Ongoing review of the literature related to safety and efficacy of ketamine and esketamine by mouth.
Psychedelic Institute of Mental Health & Family TherapyMichael DeMarco, PhD
Ketamine + Couples (Relational) Therapy & Intimacy Coaching
Psychedelic ketamine preparation, support and integration in couples, groups, families
Psychedelic Mental Health InstituteMichael DeMarco, PhD
Intimacy Coaching & Sexual Wellness & Expression
Board Certified Clinical Sexologist | Gender Affirming | Kink Aware Professional | Queer Life Coach | Ethical Non-Monogamy, Poly Relationship Coaching
Psychedelic Mental Health InstituteMichael DeMarco, PhD

Psychedelic Therapy Research

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ketamine research

Ketamine Induces Apoptosis and Inhibits Proliferation in HT-29 Colorectal Cancer Cells (Korkmaz, et al, 2026)

"findings suggest that ketamine exhibits potential anti-proliferative and pro-apoptotic effects on HT-29 colorectal cancer cells in vitro."

Aldous Huxley in 1958 on The Dictatorship of the "Future"

psychedelic research

Spotlight: N,N-dimethyltryptamine elicits antidepressant and anxiolytic effects in helpless mice: a comparative study with S-ketamine (da Sousa-Silva, et al, 2026)

DMT compared with ketamine variant, esketamine in mice.
social media addiction

Feature: Social media companies found liable in addiction cases

Meta owns Facebook, Instagram, Whatsapp and YouTube is owned by Google
ketamine harm reduction

Rational Ketamine Practice and the Current Ketamine Discourse

(Drafts ongoing)
Spotlight: "A Blueprint for Implementing Ketamine-Assisted Psychotherapy in Palliative Care: Design, Process, and Treatment Patterns of a Real-World Clinical Program" (Horowitz, et al, 2026)
psychedelic-assisted psychotherapy

Spotlight: "A Blueprint for Implementing Ketamine-Assisted Psychotherapy in Palliative Care: Design, Process, and Treatment Patterns of a Real-World Clinical Program" (Horowitz, et al, 2026)

"To our knowledge, this is the largest published cohort of KAP in an academic palliative care context. Our Pal-KAP experience suggests that KAP can be delivered safely and ethically, providing a practical blueprint for programs exploring innovative ways to address Psychospiritual distress (PSD)"
ketamine

Rapid Improvement in Consciousness After Low-Dose Ketamine in a Patient With Acute Confusion: A Case Report (Khalafallah Khalid, et al, 2025)

"While anecdotal, such findings align with emerging literature and warrant further exploration of ketamine's neurocognitive effects beyond its established indications."
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