Psychedelic Mental Health

Michael DeMarco, PhD offers psychedelic preparation, support and integration from a mind, body, heart, and spirit approach.

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Ketamine Psychedelic Preparation, Support & Integration

The Psychedelic Institute of Mental Health is a community-building and advocacy project curated by Michael DeMarco, PhD with a mission to advance psychedelic medicine practice and research by connecting therapists, researchers, coaches, retreats, and practitioners of psychedelic medicines. The Institute is YOU. Join us!

INSTITUTO PSICODÉLICO -- Un centro de estudios en psicodelia que aboga por el estudio y la práctica seguros y legales de las experiencias de la medicina psicodélica y su aplicación a la salud mental y el bienestar | Uruguay

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ketamine

Spotlight: Jeffrey Becker - The Neurobiology Underlying Transcendence Induced by Ketamine and the Psychedelics (2026)

While psychedelics selectively amplify activity in specific neural circuits, ketamine acts on a receptor found widely throughout the brain. This raises a key question: how can a drug targeting such a common receptor produce such distinct and powerful subjective effects?

04 Jul

ketamine

Spotlight: Yale presents “New Insights into the Neural Mechanisms of NMDA Receptor Antagonists Driving Rapid-Acting Antidepressant Effects” (Cichon, 2026)

"ketamine works on depression within minutes of infusion, lasting multiple days, if not weeks... amazing that it was classified as an anesthetic... twice as good as SSRI standards of care... leads to new formation of synapse, underlying sustaining mechanisms..."

26 May

Spotlight: Documentary "The Eternal Song"

Little Singer Welcome to The Eternal Song - The Eternal SongRegister to view the FULL film and gain access to the

19 May

ketamine research

Ketamine Induces Apoptosis and Inhibits Proliferation in HT-29 Colorectal Cancer Cells (Korkmaz, et al, 2026)

"findings suggest that ketamine exhibits potential anti-proliferative and pro-apoptotic effects on HT-29 colorectal cancer cells in vitro."

04 May

Aldous Huxley in 1958 on The Dictatorship of the "Future"

21 Apr

psychedelic research

Spotlight: N,N-dimethyltryptamine elicits antidepressant and anxiolytic effects in helpless mice: a comparative study with S-ketamine (da Sousa-Silva, et al, 2026)

DMT compared with ketamine variant, esketamine in mice.

26 Mar