Unfolding States of Mind: A Dissociative-Psychedelic Model of Ketamine-Assisted Psychotherapy in Palliative Care (Gonçalves Campolina & Tuena de Oliveira, 2025)
Dissociative-psychedelic model offers a compassionate, pragmatic, theoretically grounded approach to relieving psychological & existential suffering in palliative care
Spotlight: A long, strange trip: Ketamine treatment in psychiatry (Nutt, et al, 2025)
"...mystical experiences were strongly related to immediate and sustained psychiatric benefits at the group level and on an individual, session-by-session basis across the six doses, providing mechanistic support for ketamine-psychotherapy pairings."
Spotlight: Changing your mind: neuroplastic mechanisms underlying the therapeutic effect of psychedelics in depression, PTSD, and addiction (Palhas, et al, 2025)
"Serotonergic psychedelics & ketamine appear to share common cellular mechanisms. They both recruit glutamatergic neurons to stimulate BDNF-trKB signaling, promoting synaptogenesis via the mTOR pathway. These changes may explain their efficacy in depression, anxiety, PTSD, & addiction."
Spotlight: Ketamine Assisted Therapy Outcomes for First-Responders with Comorbid Mental Health Diagnoses (Tsang, et al, 2025)
"KAT may provide meaningful benefits beyond symptom reduction."
Spotlight: The transformational power of psychedelics: catalysts for creativity, consciousness, and mental health (Du, et al, 2025)
"Psychedelics, such as psilocybin, lysergic acid diethylamide (LSD), ketamine, and N,N-dimethyltryptamine (DMT), have captured the attention of scientists, artists, and seekers alike for their profound ability to alter consciousness and inspire creativity."
Spotlight: The Role of Psychedelics in Contemporary Psychological and Interdisciplinary Inquiry (Soylemez, et al, 2025)
"These compounds have been shown to enable access to unconscious cognitive and emotional content, facilitate emotional release, and induce a temporary dissolution of ego boundaries—processes that may underpin significant and enduring therapeutic outcomes."
