Psychedelic Institute of Mental Health & Family Therapy
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Spotlight: Psychedelics and mental health: reimagining care through science, insight, and compassion (Mikellides, et al, 2025)

"These substances are not stand-alone medications; rather, they function as adjuncts to intensive psychotherapeutic processes. Training therapists and establishing ethical, evidence-based protocols is essential."
Michael DeMarco, PhD

by Michael DeMarco, PhD

Frontiers | Psychedelics and mental health: reimagining care through science, insight, and compassion
Introduction In recent years, psychiatry has witnessed a renaissance in the investigation of psychedelic compounds, a broad class of psychoactive substances…
FrontiersGeorgios Mikellides

(2025) "Ketamine’s entry into psychiatric practice has paved the way for psychedelics."

Los psicodélicos y salud mental: reimaginando el cuidado a través de la ciencia, la perspicacia y la compasión

La entrada de ketaminas en la práctica psiquiátrica ha allanado el camino para los psicodélicos.

Estas sustancias no son medicamentos independientes, sino que funcionan como complementos a procesos psicoterapéuticos intensivos. La formación de terapeutas y el establecimiento de protocolos éticos basados en pruebas es esencial.

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Spotlight: Single Treatment With MM120 (Lysergide) in Generalized Anxiety DisorderA Randomized Clinical Trial (Robinson, et al, 2025)

In this phase 2b, multicenter, randomized, double-blind, placebo-controlled study of 4 dose levels of MM120 (a form of LSD) that included 198 adults with generalized anxiety disorder 4 was statistically significant.

Spotlight: Comparing the Cognitive Effects of Repeated Intravenous Ketamine and Electroconvulsive Therapy in Patients With Treatment-Resistant Depression: A Secondary Analysis of the ELEKT-D Trial

"Patients treated with ketamine demonstrated superior cognitive functioning compared with ECT following a 3-week treatment, no differences between treatments observed. Findings support short-term superiority of ketamine on cognitive functioning and the long-term cognitive safety of both treatments."
Ahora en Uruguay - una organización dedicada a la investigación, la educación y la promoción del uso de terapias asistidas con psicodélicos

Ahora en Uruguay - una organización dedicada a la investigación, la educación y la promoción del uso de terapias asistidas con psicodélicos

Nos encontramos desarrollando una iniciativa formativa orientada a profesionales en Uruguay, enfocada en el uso médico de la ketamina subanestésica para el tratamiento de condiciones como la depresión resistente, el trastorno por estrés postraumático y la ideación suicida

Spotlight: Harriet de Wit: What can we learn about behavior and brain processes by studying psychoactive drugs in humans?

"her laboratory demonstrated that MDMA enhances feelings of social connectedness during interpersonal interactions, findings that have profound implications for PTSD treatment and psychotherapy."

Spotlight: Investigating the safety and tolerability of single-dose psilocybin for post-traumatic stress disorder: A nonrandomized open-label clinical trial (McGowan, et al, 2025)

"In this trial, COMP360 psilocybin administered in a single session with psychological support was found to be generally well-tolerated and without serious risk to safety... treatment associated with rapid, sustained reduction in PTSD symptoms, improved functioning and quality of life to 12 weeks"

Spotlight: Brain changes associated with depression treatment: a meta-analysis

Meta-analysis of data from 302 depressed subjects yielding 87 foci across 18 experiments examining various depression treatments including pharmacology, psychotherapy, electroconvulsive therapy, psilocybin, and ketamine with brain activity measures in response to emotion tasks in the scanner.
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