Spotlight "Prefrontal contribution to passive coping behaviour in chronic stress and treatment by fast-acting antidepressant" (Fong, et al, 2025)
"Persistent passive coping (p-coping) behaviour is a hallmark feature in major depression and is reversed by fast-acting antidepressants (such as ketamine)."
Prefrontal contribution to passive coping behaviour in chronic stress and treatment by fast-acting antidepressant - PubMed
Persistent passive coping (p-coping) behaviour is a hallmark feature in major depression and is reversed by fast-acting antidepressants (such as ketamine). This behaviour is regulated by a specific cortico-midbrain circuit. However, the contribution of inhibition in prefrontal cortex to p-coping mod …
Tsz Hei Fong
"Contribución frontal al comportamiento pasivo de afrontamiento en el estrés crónico y tratamiento por antidepresivo de acción rápida" (Fong, et al, 2025)
El comportamiento de afrontamiento pasivo persistente (p-coping) es una característica característica en la depresión mayor y se revierte con antidepresivos de acción rápida (como la ketamina).
