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Spotlight: Ketamine and psychotherapy for the treatment of psychiatric disorders: systematic review (Kew, et al, 2023)

"...Outcomes were largely positive for the addition of psychotherapy to ketamine treatment...The combination of psychotherapy and ketamine offers promise for the treatment of psychiatric disorders"
Michael DeMarco, PhD

by Michael DeMarco, PhD

Spotlight: Ketamine and psychotherapy for the treatment of psychiatric disorders: systematic review (Kew, et al, 2023)
Ketamine and psychotherapy for the treatment of psychiatric disorders: systematic review - PMC
Ketamine is an effective short-term treatment for a range of psychiatric disorders. A key question is whether the addition of psychotherapy to ketamine treatment improves outcomes or delays relapse. To identify all studies combining psychotherapy…
NCBI home page✉Correspondence: Ben Beaglehole. Email: ben.beagleholeotago.ac.nz

(2023): "the addition of psychotherapy to ketamine treatment for psychiatric disorders is associated with largely positive outcomes and appears to offer promise.

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"the connectome harmonic repertoire under N,N-dimethyltryptamine (DMT) is reshaped in line with other reported psychedelic compounds - psilocybin, lysergic acid diethylamide (LSD) and ketamine... the repertoire entropy of connectome harmonics increases under DMT, as with those other psychedelics."
Spotlight: "Ketamine States: A Journey Through the Mind" (Wolfson, et al, 2025)

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"in a conducive set and settings, these experiences have been demonstrated to be of positive use in psychiatry and psychotherapy, providing a time-out from usual states of mind to facilitate a reshaping of self-experience along with symptomatic relief."

Spotlight: "Ketamine-Assisted Group Therapy for Work-Related Stress in First Responders and Frontline Health Care Workers" (Flynn, et al, 2025)

"Ketamine is an evidenced-based treatment for depression, and it has shown promise in addressing many other mental health conditions related to work-related stress or burnout, such as anxiety and post-traumatic stress disorder."
Spotlight: Ketamine-Occasioned Mystical Experience in Veterans with Treatment-Resistant Depression: A Retrospective Exploratory Analysis (Bhatt, et al, 2025)

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Spotlight: The Effectiveness of Combining Ketamine and Cognitive Behavioural Therapy in Treating Major Depressive Disorder (2025)

" This study seeks to investigate the combined effectiveness of ketamine and CBT in the treatment of MDD, with the hypothesis that integrated treatment will outperform either modality administered alone."
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