Rapid Improvement in Consciousness After Low-Dose Ketamine in a Patient With Acute Confusion: A Case Report (Khalafallah Khalid, et al, 2025)
"While anecdotal, such findings align with emerging literature and warrant further exploration of ketamine's neurocognitive effects beyond its established indications."
Moderating factors in psilocybin-assisted treatment affecting mood and personality: A naturalistic, open-label investigation (Irrmischer, et al, 2025)
"Findings indicate that individual psilocybin-assisted therapy has the potential for beneficial effects on mood and personality characteristics. Moreover, the study highlights the importance of subjective experiences and demographic factors in moderating this effect."
Spotlight: LSD: Mechanisms and relevance to the treatment of depression (Bouloufa, et al, 2025)
"Psychedelics may be a potential alternative therapy for treatment-resistant depression. LSD has a complex mode of action which is not yet fully understood.
Low doses of LSD can drastically increase brain plasticity."
Spotlight: The transformational power of psychedelics: catalysts for creativity, consciousness, and mental health (Du, et al, 2025)
"Psychedelics, such as psilocybin, lysergic acid diethylamide (LSD), ketamine, and N,N-dimethyltryptamine (DMT), have captured the attention of scientists, artists, and seekers alike for their profound ability to alter consciousness and inspire creativity."
Spotlight: The Role of Psychedelics in Contemporary Psychological and Interdisciplinary Inquiry (Soylemez, et al, 2025)
"These compounds have been shown to enable access to unconscious cognitive and emotional content, facilitate emotional release, and induce a temporary dissolution of ego boundaries—processes that may underpin significant and enduring therapeutic outcomes."
Spotlight: Chris Bache: LSD and the Mind of the Universe
"experiences and insights from 73 high-dose LSD sessions conducted between 1979 and 1999"
Steve Paulson