Spotlight: NPR-- Can Psychedelics Go Mainstream
"Research shows that psychedelics can help with a range of mental health conditions, like PTSD and depression. "
Michael DeMarco, PhD
Founding Fellow, Psychedelic Institute of Mental Health & Family Therapy— Ketamine psychedelic therapy preparation and integration via telehealth | California, New York, Utah, Vermont
Spotlight: "How Psychedelics Unlock Neuroplasticity for Healing"
"psychedelics open the brain to new patterns"
Spotlight: PBS Film-- The Last Ecstatic Days
A film about a young man with brain cancer in search of community, and the hospice doctor who gives up everything to honor his dying wish.
Spotlight: Safety and efficacy of ketamine for the treatment of patients with alcohol use disorder: a systematic review (Rathore, et al, 2025)
"No study reported any serious adverse event or ketamine misuse following ketamine treatment. This review underscored ketamine's potential as an adjunctive treatment for Alcohol Use Disorder."
Spotlight: Early Response to Ketamine for Suicidal Crisis Reduces Suicidal Events at 3 Months (Pastre, et al, 2025)
"This is the first study demonstrating that early SI response to IV ketamine is associated with a reduced risk of suicidal events at 3 months. These findings support ketamine's unique antisuicidal properties beyond its antidepressant effects, highlighting its potential role in suicide prevention."
uruguay
Enfoque Uruguay: Propuesta -- Estrategia Nacional de Drogas 2026-2030. Junta Nacional de Drogas
Programa Piloto de Psicoterapia Asistida con Psicodélicos en el Sistema de Salud Uruguayo | Michael DeMarco, PhD
iv ketamine
Spotlight: "Long-Term Outcomes in Patients With Treatment-Refractory Depression Receiving Intravenous Ketamine and Intranasal Esketamine: An Observational Study" (Singh, et al, 2025)
Observational study provides evidence regarding longer durability of generic IV ketamine compared to intranasal esketamine (Spravato).
Spotlight-- "Beyond Anesthesia: Ketamine's Expanding Role in Chronic Pain and Psychiatric Disorders" (Zaki, 2025)
Más allá de la anestesia: El papel de la ketamina en los trastornos crónicos del dolor y la psiquiátrica
uruguay
Propuesta para la Estrategia Nacional de Drogas 2026–2030
Programa Piloto de Psicoterapia Asistida con Psicodélicos en el Sistema de Salud Uruguayo
Spotlight: The Effects of Psychotherapy on Single and Repeated Ketamine Infusion(s) Therapy for Treatment-Resistant Depression: The Convergence of Molecular and Psychological Treatment (2025)
Ketamine's "therapeutic promise is increasingly understood to involve molecular and neurobiological processes that promote neural plasticity and cognitive flexibility. These changes may create a unique window for psychotherapeutic interventions to take deeper effect."
In Memoriam
Joyce Maureen (McGee) Koppenheffer December 9, 1947 - July 7, 2025 Rancho Mirage, California - Joyce M. Koppenheffer (née McGee) of North Kansas City, passed into the great unknown on July 7th, joining her husband Edward Koppenheffer; her former husband, Gerald Reese; her parents Weldon and Verneta McGee; and older
Spotlight: Multiday intravenous ketamine infusion therapy for the management of central sensitisation syndrome secondary to chronic chemotherapy-induced peripheral neuropathic pain (Abdullah & Ong, 2025)
...growing evidence for ketamine as an analgesic agent for chronic pain, with potential considerations to expand its use for other indications.