Ketamine was FDA approved for use in high, anesthetic doses for humans and animals in 1970, and has been studied and used off-label since then for a number of other indications also supported by cognitive behavioral psychotherapy to avoid ketamine misuse, dependence and abuse.
cbt
There are many tools to help a psychotherapist help clients learn to speak the language of cognitive behavioral therapy, especially tools which may help facilitate therapeutic alliance, including, but not limited to telehealth.
at-home ketamine
Psychedelic and psychiatric medicines have been studied for over 100 years as adjuncts to psychotherapy, with over 60 years of ongoing research on the off-label use of racemic ketamine, a generic medicine in various routes of administration with varying levels of support care
ketamine-assisted psychotherapy
"A systematic review of PO and SL ketamine noted no significant side effects, and no problems with tolerance or substance misuse in any of the studies, which totaled 140 patients who received ketamine up to 3 years in duration…” (Swainson, 2022)