uruguay
Propuesta para la Estrategia Nacional de Drogas 2026–2030
Programa Piloto de Psicoterapia Asistida con Psicodélicos en el Sistema de Salud Uruguayo
ketamine
Ketamine was FDA approved for use in high, anesthetic doses for humans and animals in 1970, and has been studied and used off-label since then for a number of other indications also supported by cognitive behavioral psychotherapy to avoid ketamine misuse, dependence and abuse.
ketamine
Spotlight: Understanding the Experience of Ketamine-Assisted Therapy and the Importance of Context (Stockwell, et al, 2025) Comprender la experiencia de la terapia asistida por ketamina y la importancia del contexto
"comfort in the setting supported participants to let go and was facilitated by learning about the therapist's personal experiences, a strong therapeutic alliance, and feeling safe...music also influenced the experience, facilitating a spiritual journey guiding the experience."
ketamine-assisted psychotherapy
Psychedelics in Palliative Care, Marcia Glass, Ed., Oxford University Press
with contributions by Psychedelic Institute fellows, Michael DeMarco, PhD and Thaís Salles Araujo, MD on ketamine, psilocybin mushrooms in palliative care
at home ketamine therapy
Spotlight: Ketamine’s Rapid Antidepressant Effects Mapped Brain-Wide + μ-opioid receptor?
"The deployment of mesoscale brain-wide fluctuation analysis unveils the complex, multiregional neural orchestration underlying ketamine’s rapid antidepressant effects, a blueprint for future therapeutic innovation... insights gained from this research hold transformative promise..."
mechanisms of action
Spotlight: Triple-network model-based graph theory analysis of the effectiveness of low-dose ketamine in patients with treatment-resistant depression: two resting-state functional MRI clinical trials (Lin, et al, 2025)
"These findings may support the utility of the triple-network model in elucidating ketamine's antidepressant effect. Alterations in DMN, salience and FPN function may underlie this effect."
ketamine
Spotlight: Rapid and sustained reduction of treatment-resistant PTSD symptoms after intravenous ketamine in a real-world, psychedelic paradigm (MacConnel, et al, 2024)
"Administering ketamine in ways that parallel psychedelic-assisted treatments—including preparatory, integration, sensory immersion, and psychotherapy sessions—could decrease PTSD symptoms meaningfully."
hallucinogen rating scale
Psychedelic Ketamine Assisted Psychotherapy & Support - Prelimary Analysis
On the the Hallucinogen Rating Scale (HRS), a widely used tool for measuring subjective effects of psychedelics and other psychoactive substances and real-world ketamine assisted therapy practice data
recovery
Spotlight: Smart Recovery & Psychedelic-Assisted Psychotherapy
On Psychedelics in Recovery
ketamine
Spotlight: Recent study finds ketamine described as having visual effects, outranking many serotonergic psychedelics and plant medicines
Ketamine was described with visual words more often than mushrooms and LSD according to a LLM analysis of Erowid data. DMT was the most described using visual words
at home ketamine
Spotlight: Ketamine Lit Review on Mastodon (a site not owned by fascists)
Over 800 posts to date! See what's new in ongoing ketamine research spanning over 60 years.
psychedelics
Neural correlates and subjective experiences in meditation vs psychedelics, including ketamine (Preliminary Lit Review)
A preliminary, evolving review of the literature. (Ongoing Draft) | Psychedelic Institute of Mental Health & Family Therapy
ketamine
Psychedelic Therapy: Does the psychedelic experience matter?
Psychedelic medicines have been studied in the Western medical literature consistently for over 100 years, over 60 of which in the ongoing study and practice of racemic ketamine. Psychedelic experiences are described similarly and often felt as profoundly meaningful.
cbt
Psychedelic Cognitive Behavioral Therapy: On Ketamine, Context, and Competencies in "Assisted-Psychotherapy”
There are many tools to help a psychotherapist help clients learn to speak the language of cognitive behavioral therapy, especially tools which may help facilitate therapeutic alliance, including, but not limited to telehealth.
at-home ketamine
Increasing Access to Psychedelic-Assisted Psychotherapy : The "proliferation of ketamine clinics" narrative and cost considerations
Psychedelic and psychiatric medicines have been studied for over 100 years as adjuncts to psychotherapy, with over 60 years of ongoing research on the off-label use of racemic ketamine, a generic medicine in various routes of administration with varying levels of support care
ketamine-assisted psychotherapy
Sublingual & Oral Ketamine Research: Efficacy, Dosage, and Treatment for Mental Health
Ongoing review of the literature related to safety and efficacy of ketamine and esketamine by mouth.