opiod system
Spotlight: Antidepressants and the endogenous opioid system (Fricker, et al, 2025)
"A growing body of evidence links the opioid system w/ major depressive disorder... two different widely used antidepressants, tianeptine & ketamine, both interact with MOR; tianeptine as a full agonist, ketamine as a positive allosteric modulator. Both produce antidepressant effects within days."
at home ketamine
Spotlight: Real-world clinical data on the long-term effectiveness and safety of generic racemic ketamine treatment (Massaneda-Tuneu, et al, 2025)
"Findings suggested that racemic ketamine (including by mouth), when appropriately dosed and administered within a structured clinical and safety monitoring framework, is both effective, safe and well-tolerated over a 6-month treatment period."
at home ketamine
Spotlight: Ketamine Harm Reduction
Prevention & Treatment in Ketamine Use Disorder - When a medicine becomes a poison
at home ketamine
Spotlight: On "Rare but relevant: Ketamine-induced cystitis - an in-depth review for addiction medicine" (Abdelrhamen, et Belal 2025) and psychedelic harm reduction, psychotherapy, support
Rare in ketamine use disorder. Rarer still in ketamine psychedelic assisted psychotherapy as prescribed by your medical provider with support from a mental health specialist, supportive cognitive behavioral therapy approaches to mental health, recovery and harm reduction.
at home ketamine
Spotlight: Ketamine Lit Review on Mastodon (a site not owned by fascists)
Over 800 posts to date! See what's new in ongoing ketamine research spanning over 60 years.
at home ketamine
Ketamine + Psychotherapy
Learn more about ketamine-assisted psychotherapy assisting you.
michael demarco therapist
About the Psychedelic Institute of Mental Health & Family Therapy
Collaborative psychotherapy in support of medicines that may affect mental health, including ketamine
psychedelic therapist joshua tree
After psychedelic therapist training? Apprenticeship Model of Practicum & Clinical Supervision helps psychedelic therapists gain valuable experience
The Psychedelic Institute of Mental Health & Family Therapy offers Psychedelic Practicum, Supervision, Apprenticeship, Clinical Consultation online in collaboration with an independent medical / psychiatric provider.
ketamine-assisted psychotherapy
Sublingual & Oral Ketamine Research: Efficacy, Dosage, and Treatment for Mental Health
Ongoing review of the literature related to safety and efficacy of ketamine and esketamine by mouth.
