Adverse Effects of Psychedelic-Assisted Psychotherapy
Dissociation in human beings is a self-reported state of mind, and no experimental technique in rodents or in humans can currently define this subjective experience in full. However, the clinically guided paradigm reported here could provide a framework of behavioural, optical and physiological tools to enable exploration of the neural activity that underlies dissociative states (Vesuna, et al, 2019).
<header class="summary-block-header">
<div class="summary-heading">
<span class="summary-header-text">Featured</span>
</div>
<div class="summary-carousel-pager sqs-gallery-controls">
<span class="summary-carousel-pager-prev previous" role="button" aria-label="Previous"></span>
<span class="summary-carousel-pager-next next" role="button" aria-label="Next"></span>
</div>
</header>
<div class="summary-item-list sqs-gallery">
<div class="
summary-item
summary-item-record-type-text
sqs-gallery-design-autocolumns-slide
summary-item-has-thumbnail
summary-item-has-cats
summary-item-has-tags
summary-item-has-author
">
<div class="summary-thumbnail-outer-container">
<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8853036/" class="
summary-thumbnail-container
sqs-gallery-image-container
">
<div class="summary-thumbnail img-wrapper">
<!-- Main Image -->
<img src="https://psychedelicmentalhealth.net/content/images/2025/03/09000-screenshot-www-ncbi_-nlm_-nih_-gov-2023-02-23-06_25_25.png" alt="Non-parenteral Ketamine for Depression: A Practical Discussion on Addiction Potential and Recommendations for Judicious Prescribing (2022)" class="summary-thumbnail-image">
</div>
<!-- Products: Quick View -->
</div>
<div class="summary-content sqs-gallery-meta-container">
<div class="summary-metadata-container summary-metadata-container--above-title">
<div class="summary-metadata summary-metadata--primary">
<!-- Timestamp -->
<time class="summary-metadata-item summary-metadata-item--date" datetime="2023-02-23">Feb 23, 2023</time>
<div class="summary-metadata summary-metadata--secondary">
<div class="summary-title">
<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8853036/" class="summary-title-link">Non-parenteral Ketamine for Depression: A Practical Discussion on Addiction Potential and Recommendations for Judicious Prescribing (2022)</a></div>
<div class="summary-metadata-container summary-metadata-container--below-title">
<div class="summary-metadata summary-metadata--primary">
<!-- Timestamp -->
<time class="summary-metadata-item summary-metadata-item--date" datetime="2023-02-23">Feb 23, 2023</time>
<div class="summary-metadata summary-metadata--secondary">
<div class="summary-metadata-container summary-metadata-container--below-content">
<div class="summary-metadata summary-metadata--primary">
<!-- Timestamp -->
<time class="summary-metadata-item summary-metadata-item--date" datetime="2023-02-23">Feb 23, 2023</time>
<div class="summary-metadata summary-metadata--secondary">
</div>
</div>
<div class="
summary-item
summary-item-record-type-text
sqs-gallery-design-autocolumns-slide
summary-item-has-thumbnail
summary-item-has-cats
summary-item-has-tags
summary-item-has-author
">
<div class="summary-thumbnail-outer-container">
<a href="https://www.ncbi.nlm.nih.gov/books/NBK470357/#_article-23876_s5_" class="
summary-thumbnail-container
sqs-gallery-image-container
">
<div class="summary-thumbnail img-wrapper">
<!-- Main Image -->
<img src="https://psychedelicmentalhealth.net/content/images/2025/03/8ab2c-screenshot-www-ncbi_-nlm_-nih_-gov-2023-02-23-06_20_56.png" alt="Adverse Effects of Ketamine " class="summary-thumbnail-image">
</div>
<!-- Products: Quick View -->
</div>
<div class="summary-content sqs-gallery-meta-container">
<div class="summary-metadata-container summary-metadata-container--above-title">
<div class="summary-metadata summary-metadata--primary">
<!-- Timestamp -->
<time class="summary-metadata-item summary-metadata-item--date" datetime="2023-02-23">Feb 23, 2023</time>
<div class="summary-metadata summary-metadata--secondary">
<div class="summary-title">
<a href="https://www.ncbi.nlm.nih.gov/books/NBK470357/#_article-23876_s5_" class="summary-title-link">Adverse Effects of Ketamine </a></div>
<div class="summary-metadata-container summary-metadata-container--below-title">
<div class="summary-metadata summary-metadata--primary">
<!-- Timestamp -->
<time class="summary-metadata-item summary-metadata-item--date" datetime="2023-02-23">Feb 23, 2023</time>
<div class="summary-metadata summary-metadata--secondary">
<div class="summary-metadata-container summary-metadata-container--below-content">
<div class="summary-metadata summary-metadata--primary">
<!-- Timestamp -->
<time class="summary-metadata-item summary-metadata-item--date" datetime="2023-02-23">Feb 23, 2023</time>
<div class="summary-metadata summary-metadata--secondary">
</div>
</div>
<div class="
summary-item
summary-item-record-type-text
sqs-gallery-design-autocolumns-slide
summary-item-has-thumbnail
summary-item-has-cats
summary-item-has-tags
summary-item-has-author
">
<div class="summary-thumbnail-outer-container">
<a href="https://pubmed.ncbi.nlm.nih.gov/35458717/" class="
summary-thumbnail-container
sqs-gallery-image-container
">
<div class="summary-thumbnail img-wrapper">
<!-- Main Image -->
<img src="https://psychedelicmentalhealth.net/content/images/2025/03/efcba-screenshot-pubmed-ncbi_-nlm_-nih_-gov-2023-02-23-06_16_17.png" alt="Psychedelics: Alternative and Potential Therapeutic Options for Treating Mood and Anxiety Disorders" class="summary-thumbnail-image">
</div>
<!-- Products: Quick View -->
</div>
<div class="summary-content sqs-gallery-meta-container">
<div class="summary-metadata-container summary-metadata-container--above-title">
<div class="summary-metadata summary-metadata--primary">
<!-- Timestamp -->
<time class="summary-metadata-item summary-metadata-item--date" datetime="2023-02-23">Feb 23, 2023</time>
<div class="summary-metadata summary-metadata--secondary">
<div class="summary-title">
<a href="https://pubmed.ncbi.nlm.nih.gov/35458717/" class="summary-title-link">Psychedelics: Alternative and Potential Therapeutic Options for Treating Mood and Anxiety Disorders</a></div>
<div class="summary-metadata-container summary-metadata-container--below-title">
<div class="summary-metadata summary-metadata--primary">
<!-- Timestamp -->
<time class="summary-metadata-item summary-metadata-item--date" datetime="2023-02-23">Feb 23, 2023</time>
<div class="summary-metadata summary-metadata--secondary">
<div class="summary-metadata-container summary-metadata-container--below-content">
<div class="summary-metadata summary-metadata--primary">
<!-- Timestamp -->
<time class="summary-metadata-item summary-metadata-item--date" datetime="2023-02-23">Feb 23, 2023</time>
<div class="summary-metadata summary-metadata--secondary">
</div>
</div>
<div class="
summary-item
summary-item-record-type-text
sqs-gallery-design-autocolumns-slide
summary-item-has-thumbnail
summary-item-has-excerpt
summary-item-has-cats
summary-item-has-tags
summary-item-has-author
">
<div class="summary-thumbnail-outer-container">
<a href="https://journals.sagepub.com/doi/full/10.1177/02698811211021588" class="
summary-thumbnail-container
sqs-gallery-image-container
">
<div class="summary-thumbnail img-wrapper">
<!-- Main Image -->
<img src="https://psychedelicmentalhealth.net/content/images/2025/03/1f3bb-screenshot-journals-sagepub-com-2023-02-18-11_33_13.png" alt="Recreational ketamine-related deaths notified to the National Programme on Substance Abuse Deaths, England, 1997–2019" class="summary-thumbnail-image">
</div>
<!-- Products: Quick View -->
</div>
<div class="summary-content sqs-gallery-meta-container">
<div class="summary-metadata-container summary-metadata-container--above-title">
<div class="summary-metadata summary-metadata--primary">
<!-- Timestamp -->
<time class="summary-metadata-item summary-metadata-item--date" datetime="2023-02-18">Feb 18, 2023</time>
<div class="summary-metadata summary-metadata--secondary">
<div class="summary-title">
<a href="https://journals.sagepub.com/doi/full/10.1177/02698811211021588" class="summary-title-link">Recreational ketamine-related deaths notified to the National Programme on Substance Abuse Deaths, England, 1997–2019</a></div>
<div class="summary-metadata-container summary-metadata-container--below-title">
<div class="summary-metadata summary-metadata--primary">
<!-- Timestamp -->
<time class="summary-metadata-item summary-metadata-item--date" datetime="2023-02-18">Feb 18, 2023</time>
<div class="summary-metadata summary-metadata--secondary">
<div class="
summary-excerpt
summary-excerpt-only
"><p class>Although the recreational use of ketamine has increased, relatively few reports of fatalities attributed to ketamine poisoning, either alone or in combination, have been documented to date. Post-mortem toxicological reports citing ketamine are uncommon, and deaths attributed to the drug are considered quite rare (<a href="https://journals.sagepub.com/doi/full/10.1177/02698811211021588#bibr193-02698811211021588"><span style="text-decoration:underline">Watterson, 2015</span></a>).</p></div>
<div class="summary-metadata-container summary-metadata-container--below-content">
<div class="summary-metadata summary-metadata--primary">
<!-- Timestamp -->
<time class="summary-metadata-item summary-metadata-item--date" datetime="2023-02-18">Feb 18, 2023</time>
<div class="summary-metadata summary-metadata--secondary">
</div>
</div>
<div class="
summary-item
summary-item-record-type-text
sqs-gallery-design-autocolumns-slide
summary-item-has-thumbnail
summary-item-has-excerpt
summary-item-has-cats
summary-item-has-tags
summary-item-has-author
">
<div class="summary-thumbnail-outer-container">
<a href="/adverse-effects-in-psychedelics-research/no-link-found-between-psychedelics-and-psychosis-cormier-2015" class="
summary-thumbnail-container
sqs-gallery-image-container
">
<div class="summary-thumbnail img-wrapper">
<!-- Main Image -->
<img src="https://psychedelicmentalhealth.net/content/images/2025/03/3fce8-screenshot-www-nature-com-2023-02-17-17_53_00.png" alt="No link found between psychedelics and psychosis (Cormier, 2015)" class="summary-thumbnail-image">
</div>
<!-- Products: Quick View -->
</div>
<div class="summary-content sqs-gallery-meta-container">
<div class="summary-metadata-container summary-metadata-container--above-title">
<div class="summary-metadata summary-metadata--primary">
<!-- Timestamp -->
<time class="summary-metadata-item summary-metadata-item--date" datetime="2023-02-18">Feb 18, 2023</time>
<div class="summary-metadata summary-metadata--secondary">
<div class="summary-title">
<a href="/adverse-effects-in-psychedelics-research/no-link-found-between-psychedelics-and-psychosis-cormier-2015" class="summary-title-link">No link found between psychedelics and psychosis (Cormier, 2015)</a></div>
<div class="summary-metadata-container summary-metadata-container--below-title">
<div class="summary-metadata summary-metadata--primary">
<!-- Timestamp -->
<time class="summary-metadata-item summary-metadata-item--date" datetime="2023-02-18">Feb 18, 2023</time>
<div class="summary-metadata summary-metadata--secondary">
<div class="
summary-excerpt
summary-excerpt-only
"><p class>“We are not claiming that no individuals have ever been harmed by psychedelics,” says author Matthew Johnson, an associate professor in the Behavioral Pharmacology Research Unit at Johns Hopkins University in Baltimore, Maryland. “Anecdotes about acid casualties can be very powerful — but these instances are rare,” he says. At the population level, he says, the data suggest that the harms of psychedelics “have been overstated”.</p></div>
<div class="summary-metadata-container summary-metadata-container--below-content">
<div class="summary-metadata summary-metadata--primary">
<!-- Timestamp -->
<time class="summary-metadata-item summary-metadata-item--date" datetime="2023-02-18">Feb 18, 2023</time>
<div class="summary-metadata summary-metadata--secondary">
</div>
</div>
<div class="
summary-item
summary-item-record-type-text
sqs-gallery-design-autocolumns-slide
summary-item-has-thumbnail
summary-item-has-excerpt
summary-item-has-cats
summary-item-has-tags
summary-item-has-author
">
<div class="summary-thumbnail-outer-container">
<a href="https://journals.sagepub.com/doi/full/10.1177/02698811211069100" class="
summary-thumbnail-container
sqs-gallery-image-container
">
<div class="summary-thumbnail img-wrapper">
<!-- Main Image -->
<img src="https://psychedelicmentalhealth.net/content/images/2025/03/23fc6-screenshot-www-nature-com-2023-02-17-17_53_00.png" alt="Adverse effects of psychedelics: From anecdotes and misinformation to systematic science (Nutt, et al, 2022)" class="summary-thumbnail-image">
</div>
<!-- Products: Quick View -->
</div>
<div class="summary-content sqs-gallery-meta-container">
<div class="summary-metadata-container summary-metadata-container--above-title">
<div class="summary-metadata summary-metadata--primary">
<!-- Timestamp -->
<time class="summary-metadata-item summary-metadata-item--date" datetime="2023-02-18">Feb 18, 2023</time>
<div class="summary-metadata summary-metadata--secondary">
<div class="summary-title">
<a href="https://journals.sagepub.com/doi/full/10.1177/02698811211069100" class="summary-title-link">Adverse effects of psychedelics: From anecdotes and misinformation to systematic science (Nutt, et al, 2022)</a></div>
<div class="summary-metadata-container summary-metadata-container--below-title">
<div class="summary-metadata summary-metadata--primary">
<!-- Timestamp -->
<time class="summary-metadata-item summary-metadata-item--date" datetime="2023-02-18">Feb 18, 2023</time>
<div class="summary-metadata summary-metadata--secondary">
<div class="
summary-excerpt
summary-excerpt-only
"><p class>This highlights the importance for clinicians and therapists to keep to the highest safety and ethical standards. It is imperative not to be overzealous and to ensure balanced media reporting to avoid future controversies, so that much needed research can continue.</p></div>
<div class="summary-metadata-container summary-metadata-container--below-content">
<div class="summary-metadata summary-metadata--primary">
<!-- Timestamp -->
<time class="summary-metadata-item summary-metadata-item--date" datetime="2023-02-18">Feb 18, 2023</time>
<div class="summary-metadata summary-metadata--secondary">
</div>
</div>
</div>