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# Spotlight: Ketamine for treatment-resistant post-traumatic stress disorder: double-blind active-controlled randomised crossover study (Beaglehole, et al, 2025)
- URL: https://psychedelicmentalhealth.net/spotlight-ketamine-for-treatment-resistant-post-traumatic-stress-disorder-double-blind-active-controlled-randomised-crossover-study-beaglehole-et-al-2025/
- Published: 2025-10-01T13:20:24.000Z
- Updated: 2025-10-01T13:20:24.000Z
- Description: "We provide preliminary support for the efficacy and tolerability of i.m. ketamine in a community sample of individuals with PTSD."
- Author: Michael DeMarco, PhD
- Tags: ketamine, im ketamine, i.m. ketamine, ketamine ptsd, ketamine therapy, ketamine research, ketamine for ptsd, ketamine-assisted therapy

[Ketamine for treatment-resistant post-traumatic stress disorder: double-blind active-controlled randomised crossover study - PubMedWe provide preliminary support for the efficacy and tolerability of i.m. ketamine in a community sample of individuals with PTSD. Further work is required to establish the optimal dosing regimen and longer-term role of ketamine in treatment of PTSD, but our findings are encouraging given the well-kn …![](https://storage.ghost.io/c/61/a8/61a8484e-df24-47fb-903c-d012ff10c983/content/images/icon/favicon-192-117.png)PubMedBen Beaglehole![](https://storage.ghost.io/c/61/a8/61a8484e-df24-47fb-903c-d012ff10c983/content/images/thumbnail/pubmed-meta-image-v2-116.jpg)](https://pubmed.ncbi.nlm.nih.gov/41030011/)

(2025): "We provide preliminary support for the efficacy and tolerability of i.m. ketamine in a community sample of individuals with PTSD."