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# Spotlight: From Anesthetic to Neuroprotector: Multi-Omics Reveals Ketamine's Previously Unexplored Neuroprotective Role in Alzheimer's Disease (Gong, et al, 2025)
- URL: https://psychedelicmentalhealth.net/spotlight-from-anesthetic-to-neuroprotector-multi-omics-reveals-ketamines-previously-unexplored-neuroprotective-role-in-alzheimers-disease-gong-et-al-2025/
- Published: 2025-09-05T11:33:43.000Z
- Updated: 2025-09-05T11:33:43.000Z
- Description: "This integrative study identifies robust diagnostic biomarkers and nominates ketamine for repurposing in AD. Experimental validation of ketamine's neuroprotective effects and FIBP's role is warranted."
- Author: Michael DeMarco, PhD
- Tags: ketamine, neuroprotective, alzheimer's disease, ketamine research, brains, research, psychedelic research

[From Anesthetic to Neuroprotector: Multi-Omics Reveals Ketamine’s Previously Unexplored Neuroprotective Role in Alzheimer’s Disease - PubMedThis integrative study identifies robust diagnostic biomarkers and nominates ketamine for repurposing in AD. Experimental validation of ketamine’s neuroprotective effects and FIBP’s role is warranted.![](https://storage.ghost.io/c/61/a8/61a8484e-df24-47fb-903c-d012ff10c983/content/images/icon/favicon-192-91.png)PubMedYue Gong![](https://storage.ghost.io/c/61/a8/61a8484e-df24-47fb-903c-d012ff10c983/content/images/thumbnail/pubmed-meta-image-v2-90.jpg)](https://pubmed.ncbi.nlm.nih.gov/40908685/)

2025: CASP6, LDHA, and CHRM1 underpin immune-metabolic dysregulation in AD. Ketamine targets these genes, suggesting therapeutic potential. FIBP's protective role and naive B-cell shifts offer novel mechanistic insights.