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# Rapid Improvement in Consciousness After Low-Dose Ketamine in a Patient With Acute Confusion: A Case Report (Khalafallah Khalid, et al, 2025)
- URL: https://psychedelicmentalhealth.net/rapid-improvement-in-consciousness-after-low-dose-ketamine-in-a-patient-with-acute-confusion-a-case-report-khalafallah-khalid-et-al-2025/
- Published: 2026-01-11T19:18:30.000Z
- Updated: 2026-01-11T19:18:30.000Z
- Description: "While anecdotal, such findings align with emerging literature and warrant further exploration of ketamine's neurocognitive effects beyond its established indications."
- Author: Michael DeMarco, PhD
- Tags: ketamine, UTI, ketamine research, iv ketamine, consciousness, neuroprotective, neurocognitive

[Rapid Improvement in Consciousness After Low-Dose Ketamine in a Patient With Acute Confusion: A Case Report - PubMedKetamine, widely used for procedural sedation, may possess underrecognized neuroprotective and cognitive-modulating effects. We report the case of a 66-year-old female patient who presented with acute confusion (Glasgow Coma Scale (GCS) 12/15; E3V4M5), likely secondary to a urinary tract infection. …![](https://storage.ghost.io/c/61/a8/61a8484e-df24-47fb-903c-d012ff10c983/content/images/icon/favicon-192-138.png)PubMedWaleed Khalid Khalafallah Khalid![](https://storage.ghost.io/c/61/a8/61a8484e-df24-47fb-903c-d012ff10c983/content/images/thumbnail/pubmed-meta-image-v2-137.jpg)](https://pubmed.ncbi.nlm.nih.gov/41503318/)

In case of older adult presenting with confusion due to urinary tract infection regaining consciousness after a 40 minute IV-ketamine treatment (2025): "While anecdotal, such findings align with emerging literature and warrant further exploration of ketamine's neurocognitive effects beyond its established indications."