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# Psychedelics and mental health: reimagining care through science, insight, and compassion  (Mikellides, et al, 2025)
- URL: https://psychedelicmentalhealth.net/psychedelics-ketamine-mental-health-reimagining-care-through-science-insight-and-compassion-mikellides-et-al-2025/
- Published: 2025-09-19T11:50:48.000Z
- Updated: 2025-09-19T11:50:48.000Z
- Description: "These substances are not stand-alone medications; rather, they function as adjuncts to intensive psychotherapeutic processes. Training therapists and establishing ethical, evidence-based protocols is essential."
- Author: Michael DeMarco, PhD
- Tags: ketamine, is ketamine a psychedelic, ketamine research, psychedelic research, psychedelics, mental health, psychedelic assisted psychotherapy, ketamine-assisted psychotherapy

[Frontiers | Psychedelics and mental health: reimagining care through science, insight, and compassionIntroduction In recent years, psychiatry has witnessed a renaissance in the investigation of psychedelic compounds, a broad class of psychoactive substances…![](https://storage.ghost.io/c/61/a8/61a8484e-df24-47fb-903c-d012ff10c983/content/images/icon/favicon_32-tenantFavicon-Frontiers-5.png)FrontiersGeorgios Mikellides![](https://storage.ghost.io/c/61/a8/61a8484e-df24-47fb-903c-d012ff10c983/content/images/thumbnail/WebsiteWebP_XL-FPHAR_Main-20Visual_Purple_Website-1.webp)](https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2025.1649929/full)

(2025):"non-traditional therapies, such as ketamine-assisted psychotherapy, demonstrate both safety and efficacy in treatment-resistant populations. Ketamine induces altered states of consciousness that have shown transformative psychological effects in some patients. Building on this, the field is now exploring classic psychedelics like psilocybin and LSD, which may offer even deeper transpersonal experiences and long-lasting therapeutic benefits."